Library
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Protamine zinc (PZI) insulin (brand name Prozinc®) is an injectable medication approved for use in cats and dogs with diabetes mellitus. It is used to lower blood sugar levels and for long-term maintenance therapy of diabetes mellitus. This medication may be used “off label” or “extra label” in other species. Monitor closely for signs of low blood sugar (weakness, lack of energy, lethargy, stumbling or difficulty walking, behavior changes, muscle twitching, seizures, and/or unresponsiveness).
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Interferon alfa is given by mouth or injection and is used off label to treat certain viral diseases in dogs and cats. Give as directed by your veterinarian. Side effects are uncommon but may include vomiting or decreased appetite. Do not use in pets that are allergic to it or that are receiving immediate vaccination. If a negative reaction occurs, please call your veterinary office.
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Isoflupredone combinations topical are combination medications containing isoflupredone (a corticosteroid) and other medications. Isoflupredone may be compounded with an antibiotic, a local anesthetic, or other medications to treat surface skin conditions where use of a steroid combination product is indicated. Its use may off label (extra label) depending on the species, condition(s) being treated, and formulation. Isoflupredone combinations topical come in powder and ointment forms, often specially compounded.
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Isoxsuprine is a vasodilator that relaxes blood vessel walls outside of major organs. It has been used to help treat frostbite in birds and in certain conditions in dogs. It is used “off label” or “extra label” in animals. Isoxsuprine comes in tablet and powder forms. Avoid use in animals who have recently given birth or have bleeding.
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Itraconazole is given by mouth in the form of a capsule, tablet, or liquid to treat fungal infections in cats and for off-label treatment in dogs and small mammals. The most common side effects are anorexia, vomiting, liver toxicity, skin lesions, or limb and vessel swelling. It should not be used in pets with liver disease or low stomach acid production, and used with caution in pregnant, lactating, or pets with heart disease.
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Ivermectin is most used as a heartworm preventive in dogs and cats. It is also used off label for treating a variety of internal and external parasites. Ivermectin may be combined with other deworming medications. Ivermectin is available as tablets, chewable tablets, a topical liquid (for ear mite treatments), and an injectable that your veterinarian will administer.
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Ivermectin + pyrantel is a heartworm disease preventive that treats and controls hookworms and roundworms in dogs. Ivermectin + pyrantel is given by mouth as a flavored chew tablet. At prescribed doses, ivermectin + pyrantel is well-tolerated. Some dog breeds (e.g., collies, sheepdogs, and collie- or sheepdog-cross breeds) are more sensitive to ivermectin than others; your veterinarian will advise you on the safety of using this medication in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.
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Ivermectin + pyrantel + praziquantel is a combination of anti-parasitic medications used to prevent heartworms and control roundworm, hookworm, and tapeworm in dogs. It is given by mouth as a flavored chew tablet. At prescribed doses, this product is generally well-tolerated but some dogs may experience decreased appetite, vomiting, diarrhea, or burping. Certain drugs may interact with those in this combination product; it is extremely important to let your veterinarian know about any medications or supplements that your pet is taking. If your dog has an adverse reaction to this product, call your veterinary office immediately.
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This handout outlines the use of disease-modifying osteoarthritis drugs (DMOADs) in cats, specifically the use of polysulfated glycosaminoglycans (PSGAGs). The rationale for their use, potential side effects, and treatment expectations are explained.
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Kaolin/pectin is given by mouth and is used off label to treat diarrhea and certain toxicities. Use as directed by your veterinarian. Side effects are uncommon, but constipation is possible (rarely). Do not use in pets that are allergic to it, or to control severe diarrhea or diarrhea that is caused by an infection. Do not use the combination product that includes bismuth subsalicylate in cats. If a negative reaction occurs, please call your veterinary office.